Ontology highlight
ABSTRACT:
SUBMITTER: Chauhan S
PROVIDER: S-EPMC6127855 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Chauhan Sitara S Danielson Steven S Clements Virginia V Edwards Nathan N Ostrand-Rosenberg Suzanne S Fenselau Catherine C
Journal of proteome research 20161020 1
In this report, we use a proteomic strategy to identify glycoproteins on the surface of exosomes derived from myeloid-derived suppressor cells (MDSCs), and then test if selected glycoproteins contribute to exosome-mediated chemotaxis and migration of MDSCs. We report successful modification of a surface chemistry method for use with exosomes and identify 21 surface N-glycoproteins on exosomes released by mouse mammary carcinoma-induced MDSCs. These glycoprotein identities and functionalities are ...[more]