Ontology highlight
ABSTRACT:
SUBMITTER: Evola CM
PROVIDER: S-EPMC6128413 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Evola Christopher M CM Hudson Tanner L TL Huang Luping L Corbett Adrian M AM Mayes Debra A DA
Aging 20180801 8
Recently epidemiological studies suggest females lose neuroprotection from neurodegenerative diseases as they go through menopause. It has been hypothesized that this neuroprotection is hormone-dependent. The current study characterized cell signaling molecules downstream of estrogen receptor beta that are known to play a role in memory, PKC, ERK, and connexin-43, in regions of the brain associated with memory decline in an attempt to elucidate significant changes that occur post-estrus. Total w ...[more]