Ontology highlight
ABSTRACT:
SUBMITTER: Xue X
PROVIDER: S-EPMC6128896 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Xue Xiangdong X Huang Yee Y Bo Ruonan R Jia Bei B Wu Hao H Yuan Ye Y Wang Zhongling Z Ma Zhao Z Jing Di D Xu Xiaobao X Yu Weimin W Lin Tzu-Yin TY Li Yuanpei Y
Nature communications 20180907 1
Nanotheranostics with integrated diagnostic and therapeutic functions show exciting potentials towards precision nanomedicine. However, targeted delivery of nanotheranostics is hindered by several biological barriers. Here, we report the development of a dual size/charge- transformable, Trojan-Horse nanoparticle (pPhD NP) for delivery of ultra-small, full active pharmaceutical ingredients (API) nanotheranostics with integrated dual-modal imaging and trimodal therapeutic functions. pPhD NPs exhib ...[more]