Comparative analysis of tissue reconstruction algorithms for 3D histology.
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ABSTRACT:
SUBMITTER: Kartasalo K
PROVIDER: S-EPMC6129300 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Publications
Comparative analysis of tissue reconstruction algorithms for 3D histology.
Kartasalo Kimmo K Latonen Leena L Vihinen Jorma J Visakorpi Tapio T Nykter Matti M Ruusuvuori Pekka P
Bioinformatics (Oxford, England) 20180901 17
<h4>Motivation</h4>Digital pathology enables new approaches that expand beyond storage, visualization or analysis of histological samples in digital format. One novel opportunity is 3D histology, where a three-dimensional reconstruction of the sample is formed computationally based on serial tissue sections. This allows examining tissue architecture in 3D, for example, for diagnostic purposes. Importantly, 3D histology enables joint mapping of cellular morphology with spatially resolved omics da ...[more]
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