Ontology highlight
ABSTRACT:
SUBMITTER: Kumbhare D
PROVIDER: S-EPMC6130053 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Kumbhare Deepak D Kumbhare Deepak D Palys Viktoras V Toms Jamie J Wickramasinghe Chathurika S CS Amarasinghe Kasun K Manic Milos M Hughes Evan E Holloway Kathryn L KL
Frontiers in neuroscience 20180903
Deep brain stimulation (DBS) of nucleus basalis of Meynert (NBM) is currently being evaluated as a potential therapy to improve memory and overall cognitive function in dementia. Although, the animal literature has demonstrated robust improvement in cognitive functions, phase 1 trial results in humans have not been as clear-cut. We hypothesize that this may reflect differences in electrode location within the NBM, type and timing of stimulation, and the lack of a biomarker for determining the st ...[more]