Ontology highlight
ABSTRACT:
SUBMITTER: Peng L
PROVIDER: S-EPMC6130218 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Peng Liang L Linghu Ruixia R Chen Demeng D Yang Jing J Kou Xiaoxue X Wang Xiang-Zhen XZ Hu Yi Y Jiang Yi-Zhou YZ Yang Junlan J
Experimental & molecular medicine 20170421 4
Esophageal squamous cell carcinoma (ESCC) is a deadly malignancy with regard to mortality and prognosis, and the 5-year survival rate for all patients diagnosed with ESCC remains poor. A better understanding of the biological mechanisms of ESCC tumorigenesis and progression is of great importance to improve treatment of this disease. In this study, we demonstrated that the glutathione metabolism pathway is highly enriched in ESCC cells compared with normal esophageal epithelial cells in an in vi ...[more]