Ontology highlight
ABSTRACT:
SUBMITTER: Liu C
PROVIDER: S-EPMC6130602 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Liu Chaoyue C Wright Benjamin B Allen-Vercoe Emma E Gu Hong H Beiko Robert R
Genome biology and evolution 20180901 9
Homologous genes in prokaryotes can be described using phylogenetic profiles which summarize their patterns of presence or absence across a set of genomes. Phylogenetic profiles have been used for nearly twenty years to cluster genes based on measures such as the Euclidean distance between profile vectors. However, most approaches do not take into account the phylogenetic relationships amongst the profiled genomes, and overrepresentation of certain taxonomic groups (i.e., pathogenic species with ...[more]