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Identification of a Bromodomain-containing Protein 2 (BRD2) Gene Polymorphic Variant and Its Effects on Pork Quality Traits in Berkshire Pigs.


ABSTRACT: Bromodomain-containing protein 2 (BRD2) is a nuclear serine/threonine kinase involved in transcriptional regulation. We investigated the expression and association of the BRD2 gene as a candidate gene for meat quality traits in Berkshire pigs. BRD2 mRNA was expressed at relatively high levels in muscle tissue. Statistical analysis revealed that the c.1709G>C polymorphism of the BRD2 gene was significantly associated with carcass weight, meat color (a*, redness), protein content, cooking loss, water-holding capacity, carcass temperatures 4, 12 and 24 h postmortem, and the 24 h postmortem pH in 384 Berkshire pigs. Therefore, this polymorphism in the porcine BRD2 gene may be used as a candidate genetic marker to improve meat quality traits in pigs.

SUBMITTER: Lee DJ 

PROVIDER: S-EPMC6131382 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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Identification of a Bromodomain-containing Protein 2 <i>(BRD2)</i> Gene Polymorphic Variant and Its Effects on Pork Quality Traits in Berkshire Pigs.

Lee Dong Ju DJ   Hwang Jung Hye JH   Ha Jeongim J   Yu Go Eun GE   Kwon Seulgi S   Park Da Hye DH   Kang Deok Gyeong DG   Kim Tae Wan TW   Park Hwa Chun HC   An Sang Mi SM   Kim Chul Wook CW  

Korean journal for food science of animal resources 20180930 4


Bromodomain-containing protein 2 <i>(BRD2)</i> is a nuclear serine/threonine kinase involved in transcriptional regulation. We investigated the expression and association of the <i>BRD2</i> gene as a candidate gene for meat quality traits in Berkshire pigs. <i>BRD2</i> mRNA was expressed at relatively high levels in muscle tissue. Statistical analysis revealed that the c.1709G>C polymorphism of the <i>BRD2</i> gene was significantly associated with carcass weight, meat color (a*, redness), prote  ...[more]

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