Interaction between known risk factors for head and neck cancer and socioeconomic status: the Carolina Head and Neck Cancer Study.

ABSTRACT: Prior studies of squamous cell carcinoma of the head and neck (SCCHN) have explored the effect of socioeconomic status (SES) as an independent risk factor; however, none have investigated the interaction of known risk factors with SES. We examined this using the North Carolina Head and Neck Cancer Epidemiology Study, a population-based case-control study. Incident cases of SCCHN from North Carolina between 2002 and 2006 (n?=?1,153) were identified and age, sex, and race-matched controls (n?=?1,267) were selected from driver license records. SES measures included household income, educational attainment, and health insurance. Logistic regression was used to estimate adjusted odds ratios (OR) and 95% confidence intervals (CI). Current smoking was more strongly associated with SCCHN among those households making ?$50,000/year [OR 2.47 (1.69-3.25); p interaction??$50,000/year [1.28 (0.97-1.58); p interaction?

SUBMITTER: Stanford-Moore G 

PROVIDER: S-EPMC6133180 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature