Unknown

Dataset Information

0

Short-Term (<8 wk) High-Intensity Interval Training in Diseased Cohorts.


ABSTRACT:

Background and aim

Exercise training regimes can lead to improvements in measures of cardiorespiratory fitness (CRF), improved general health, and reduced morbidity and overall mortality risk. High-intensity interval training (HIIT) offers a time-efficient approach to improve CRF in healthy individuals, but the relative benefits of HIIT compared with traditional training methods are unknown in across different disease cohorts.

Methods

This systematic review and meta-analysis compares CRF gains in randomized controlled trials of short-term (<8 wk) HIIT versus either no exercise control (CON) or moderate continuous training (MCT) within diseased cohorts. Literature searches of the following databases were performed: MEDLINE, EMBASE, CINAHL, AMED, and PubMed (all from inception to December 1, 2017), with further searches of Clinicaltrials.gov and citations via Google Scholar. Primary outcomes were effect on CRF variables: V˙O2peak and anaerobic threshold.

Results

Thirty-nine studies met the inclusion criteria. HIIT resulted in a clinically significant increase in V˙O2peak compared with CON (mean difference [MD] = 3.32 mL·kg·min, 95% confidence interval [CI] = 2.56-2.08). Overall HIIT provided added benefit to V˙O2peak over MCT (MD = 0.79 mL·kg·min, 95% CI = 0.20-1.39). The benefit of HIIT was most marked in patients with cardiovascular disease when compared with MCT (V˙O2peak: MD = 1.66 mL·kg·min, 95% CI = 0.60-2.73; anaerobic threshold: MD = 1.61 mL·kg·min, 95% CI = 0.33-2.90).

Conclusions

HIIT elicits improvements in objective measures of CRF within 8 wk in diseased cohorts compared with no intervention. When compared with MCT, HIIT imparts statistically significant additional improvements in measures of CRF, with clinically important additional improvements in V˙O2peak in cardiovascular patients. Comparative efficacy of HIIT versus MCT combined with an often reduced time commitment may warrant HIIT's promotion as a viable clinical exercise intervention.

SUBMITTER: Blackwell JEM 

PROVIDER: S-EPMC6133203 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

altmetric image

Publications

Short-Term (<8 wk) High-Intensity Interval Training in Diseased Cohorts.

Blackwell James E M JEM   Doleman Brett B   Herrod Philip J J PJJ   Ricketts Samuel S   Phillips Bethan E BE   Lund Jonathan N JN   Williams John P JP  

Medicine and science in sports and exercise 20180901 9


<h4>Background and aim</h4>Exercise training regimes can lead to improvements in measures of cardiorespiratory fitness (CRF), improved general health, and reduced morbidity and overall mortality risk. High-intensity interval training (HIIT) offers a time-efficient approach to improve CRF in healthy individuals, but the relative benefits of HIIT compared with traditional training methods are unknown in across different disease cohorts.<h4>Methods</h4>This systematic review and meta-analysis compa  ...[more]

Similar Datasets

| S-EPMC9306492 | biostudies-literature
| S-EPMC6771883 | biostudies-literature
| S-EPMC8991597 | biostudies-literature
2021-09-01 | GSE163356 | GEO
| S-EPMC7071177 | biostudies-literature
2024-05-30 | GSE268211 | GEO
| S-EPMC8349982 | biostudies-literature
| S-EPMC10749735 | biostudies-literature
| S-EPMC7489382 | biostudies-literature
| S-EPMC5875631 | biostudies-literature