Ontology highlight
ABSTRACT:
SUBMITTER: Coussement L
PROVIDER: S-EPMC6133922 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Coussement Louis L Bolca Selin S Van Criekinge Wim W Trooskens Geert G Mensaert Klaas K Poels Katrien K Roche Nathalie N Blondeel Phillip P Godderis Lode L Depypere Herman H De Meyer Tim T
Scientific reports 20180911 1
Upon soy consumption, isoflavone metabolites attain bioactive concentrations in breast tissue possibly affecting health. Though in vitro epigenetic activity of soy metabolites has been described, the in vivo impact on the epigenome is largely unknown. Therefore, in this case-control study, the breast glandular tissue DNA methylome was explored in women undergoing an aesthetic breast reduction. After a run-in phase, 10 generally healthy Belgian or Dutch women received soymilk for 5 days. MethylCa ...[more]