Ontology highlight
ABSTRACT:
SUBMITTER: Jeong M
PROVIDER: S-EPMC6134051 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Jeong Minjin M O'Reilly Molly M Kirkwood Nerissa K NK Al-Aama Jumana J Lako Majlinda M Kros Corné J CJ Armstrong Lyle L
Cell death & disease 20180911 9
In view of the prevalence of sensorineural hearing defects in an ageing population, the development of protocols to generate cochlear hair cells and their associated sensory neurons as tools to further our understanding of inner ear development are highly desirable. We report herein a robust protocol for the generation of both vestibular and cochlear hair cells from human pluripotent stem cells which represents an advance over currently available methods that have been reported to generate vesti ...[more]