Ontology highlight
ABSTRACT:
SUBMITTER: Strakova J
PROVIDER: S-EPMC6134145 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Strakova Jana J Kamdar Forum F Kulhanek Debra D Razzoli Maria M Garry Daniel J DJ Ervasti James M JM Bartolomucci Alessandro A Townsend DeWayne D
Scientific reports 20180911 1
Duchenne muscular dystrophy (DMD) is a disease marked by the development of skeletal muscle weakness and wasting. DMD results from mutations in the gene for the cytoskeletal protein dystrophin. The loss of dystrophin expression is not limited to muscle weakness but has multiple systemic consequences. Managing the nutritional requirements is an important aspect of the clinical care of DMD patients and is complicated by the poor understanding of the role of dystrophin, and dystrophic processes, in ...[more]