Ontology highlight
ABSTRACT:
SUBMITTER: Gagliardi G
PROVIDER: S-EPMC6135113 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Gagliardi Giuliana G Ben M'Barek Karim K Chaffiol Antoine A Slembrouck-Brec Amélie A Conart Jean-Baptiste JB Nanteau Céline C Rabesandratana Oriane O Sahel José-Alain JA Duebel Jens J Orieux Gael G Reichman Sacha S Goureau Olivier O
Stem cell reports 20180809 3
Photoreceptor degenerative diseases are a major cause of blindness for which cell replacement is one of the most encouraging strategies. For stem cell-based therapy using human induced pluripotent stem cells (hiPSCs), it is crucial to obtain a homogenous photoreceptor cell population. We confirmed that the cell surface antigen CD73 is exclusively expressed in hiPSC-derived photoreceptors by generating a fluorescent cone rod homeobox (Crx) reporter hiPSC line using CRISPR/Cas9 genome editing. We ...[more]