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Single fraction of accelerated partial breast irradiation in the elderly: early clinical outcome.

ABSTRACT: BACKGROUND:To analyze the clinical outcome of elderly women with early breast cancer who underwent accelerated partial breast irradiation (APBI) based on a post-operative single fraction of multicatheter interstitial high dose-rate brachytherapy (MIB). METHODS:A single institution retrospective cohort study was performed focusing on elderly patients (? 65 years old) presenting a low-risk breast carcinoma treated by lumpectomy plus axillary evaluation followed by MIB. A single fraction of 16 Gy was prescribed on the 100% isodose. Clinical outcome at 3 years was reported based on local relapse free survival (3-y LRFS), specific survival (SS) and overall survival (OS). Acute (

SUBMITTER: Kinj R 

PROVIDER: S-EPMC6136182 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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Single fraction of accelerated partial breast irradiation in the elderly: early clinical outcome.

Kinj Rémy R   Chand Marie-Eve ME   Gal Jocelyn J   Gautier Mathieu M   Montagné Lucile L   Lam Cham Kee Daniel D   Hannoun-Lévi Jean Michel JM  

Radiation oncology (London, England) 20180912 1

<h4>Background</h4>To analyze the clinical outcome of elderly women with early breast cancer who underwent accelerated partial breast irradiation (APBI) based on a post-operative single fraction of multicatheter interstitial high dose-rate brachytherapy (MIB).<h4>Methods</h4>A single institution retrospective cohort study was performed focusing on elderly patients (≥ 65 years old) presenting a low-risk breast carcinoma treated by lumpectomy plus axillary evaluation followed by MIB. A single frac  ...[more]

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