Ontology highlight
ABSTRACT:
SUBMITTER: Roselli C
PROVIDER: S-EPMC6136836 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Roselli Carolina C Chaffin Mark D MD Weng Lu-Chen LC Aeschbacher Stefanie S Ahlberg Gustav G Albert Christine M CM Almgren Peter P Alonso Alvaro A Anderson Christopher D CD Aragam Krishna G KG Arking Dan E DE Barnard John J Bartz Traci M TM Benjamin Emelia J EJ Bihlmeyer Nathan A NA Bis Joshua C JC Bloom Heather L HL Boerwinkle Eric E Bottinger Erwin B EB Brody Jennifer A JA Calkins Hugh H Campbell Archie A Cappola Thomas P TP Carlquist John J Chasman Daniel I DI Chen Lin Y LY Chen Yii-Der Ida YI Choi Eue-Keun EK Choi Seung Hoan SH Christophersen Ingrid E IE Chung Mina K MK Cole John W JW Conen David D Cook James J Crijns Harry J HJ Cutler Michael J MJ Damrauer Scott M SM Daniels Brian R BR Darbar Dawood D Delgado Graciela G Denny Joshua C JC Dichgans Martin M Dörr Marcus M Dudink Elton A EA Dudley Samuel C SC Esa Nada N Esko Tonu T Eskola Markku M Fatkin Diane D Felix Stephan B SB Ford Ian I Franco Oscar H OH Geelhoed Bastiaan B Grewal Raji P RP Gudnason Vilmundur V Guo Xiuqing X Gupta Namrata N Gustafsson Stefan S Gutmann Rebecca R Hamsten Anders A Harris Tamara B TB Hayward Caroline C Heckbert Susan R SR Hernesniemi Jussi J Hocking Lynne J LJ Hofman Albert A Horimoto Andrea R V R ARVR Huang Jie J Huang Paul L PL Huffman Jennifer J Ingelsson Erik E Ipek Esra Gucuk EG Ito Kaoru K Jimenez-Conde Jordi J Johnson Renee R Jukema J Wouter JW Kääb Stefan S Kähönen Mika M Kamatani Yoichiro Y Kane John P JP Kastrati Adnan A Kathiresan Sekar S Katschnig-Winter Petra P Kavousi Maryam M Kessler Thorsten T Kietselaer Bas L BL Kirchhof Paulus P Kleber Marcus E ME Knight Stacey S Krieger Jose E JE Kubo Michiaki M Launer Lenore J LJ Laurikka Jari J Lehtimäki Terho T Leineweber Kirsten K Lemaitre Rozenn N RN Li Man M Lim Hong Euy HE Lin Henry J HJ Lin Honghuang H Lind Lars L Lindgren Cecilia M CM Lokki Marja-Liisa ML London Barry B Loos Ruth J F RJF Low Siew-Kee SK Lu Yingchang Y Lyytikäinen Leo-Pekka LP Macfarlane Peter W PW Magnusson Patrik K PK Mahajan Anubha A Malik Rainer R Mansur Alfredo J AJ Marcus Gregory M GM Margolin Lauren L Margulies Kenneth B KB März Winfried W McManus David D DD Melander Olle O Mohanty Sanghamitra S Montgomery Jay A JA Morley Michael P MP Morris Andrew P AP Müller-Nurasyid Martina M Natale Andrea A Nazarian Saman S Neumann Benjamin B Newton-Cheh Christopher C Niemeijer Maartje N MN Nikus Kjell K Nilsson Peter P Noordam Raymond R Oellers Heidi H Olesen Morten S MS Orho-Melander Marju M Padmanabhan Sandosh S Pak Hui-Nam HN Paré Guillaume G Pedersen Nancy L NL Pera Joanna J Pereira Alexandre A Porteous David D Psaty Bruce M BM Pulit Sara L SL Pullinger Clive R CR Rader Daniel J DJ Refsgaard Lena L Ribasés Marta M Ridker Paul M PM Rienstra Michiel M Risch Lorenz L Roden Dan M DM Rosand Jonathan J Rosenberg Michael A MA Rost Natalia N Rotter Jerome I JI Saba Samir S Sandhu Roopinder K RK Schnabel Renate B RB Schramm Katharina K Schunkert Heribert H Schurman Claudia C Scott Stuart A SA Seppälä Ilkka I Shaffer Christian C Shah Svati S Shalaby Alaa A AA Shim Jaemin J Shoemaker M Benjamin MB Siland Joylene E JE Sinisalo Juha J Sinner Moritz F MF Slowik Agnieszka A Smith Albert V AV Smith Blair H BH Smith J Gustav JG Smith Jonathan D JD Smith Nicholas L NL Soliman Elsayed Z EZ Sotoodehnia Nona N Stricker Bruno H BH Sun Albert A Sun Han H Svendsen Jesper H JH Tanaka Toshihiro T Tanriverdi Kahraman K Taylor Kent D KD Teder-Laving Maris M Teumer Alexander A Thériault Sébastien S Trompet Stella S Tucker Nathan R NR Tveit Arnljot A Uitterlinden Andre G AG Van Der Harst Pim P Van Gelder Isabelle C IC Van Wagoner David R DR Verweij Niek N Vlachopoulou Efthymia E Völker Uwe U Wang Biqi B Weeke Peter E PE Weijs Bob B Weiss Raul R Weiss Stefan S Wells Quinn S QS Wiggins Kerri L KL Wong Jorge A JA Woo Daniel D Worrall Bradford B BB Yang Pil-Sung PS Yao Jie J Yoneda Zachary T ZT Zeller Tanja T Zeng Lingyao L Lubitz Steven A SA Lunetta Kathryn L KL Ellinor Patrick T PT
Nature genetics 20180611 9
Atrial fibrillation (AF) affects more than 33 million individuals worldwide<sup>1</sup> and has a complex heritability<sup>2</sup>. We conducted the largest meta-analysis of genome-wide association studies (GWAS) for AF to date, consisting of more than half a million individuals, including 65,446 with AF. In total, we identified 97 loci significantly associated with AF, including 67 that were novel in a combined-ancestry analysis, and 3 that were novel in a European-specific analysis. We sought ...[more]