Ontology highlight
ABSTRACT:
SUBMITTER: Sangalli JR
PROVIDER: S-EPMC6137158 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Sangalli Juliano Rodrigues JR Sampaio Rafael Vilar RV Del Collado Maite M da Silveira Juliano Coelho JC De Bem Tiago Henrique Camara THC Perecin Felipe F Smith Lawrence Charles LC Meirelles Flávio Vieira FV
Scientific reports 20180913 1
The rapid decline in fertility that has been occurring to high-producing dairy cows in the past 50 years seems to be associated with metabolic disturbances such as ketosis, supporting the need for research to improve our understanding of the relations among the diet, metabolism and embryonic development. Recently, the ketone body β-hydroxybutyrate (BOHB) was demonstrated to be a potent inhibitor of histone deacetylases (HDACs). Herein, we performed a series of experiments aiming to investigate t ...[more]