Ontology highlight
ABSTRACT:
SUBMITTER: Chang TT
PROVIDER: S-EPMC6137544 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Chang Tammy T TT Spurlock Sandra M SM Candelario Tara Lynne T TL Grenon S Marlene SM Hughes-Fulford Millie M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20150617 10
The health risks of a dysregulated immune response during spaceflight are important to understand as plans emerge for humans to embark on long-term space travel to Mars. In this first-of-its-kind study, we used adoptive transfer of T-cell receptor transgenic OT-II CD4 T cells to track an in vivo antigen-specific immune response that was induced during the course of spaceflight. Experimental mice destined for spaceflight and mice that remained on the ground received transferred OT-II cells and co ...[more]