TMCrys: predict propensity of success for transmembrane protein crystallization.
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ABSTRACT:
SUBMITTER: Varga JK
PROVIDER: S-EPMC6137969 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Publications
TMCrys: predict propensity of success for transmembrane protein crystallization.
Varga Julia K JK Tusnády Gábor E GE
Bioinformatics (Oxford, England) 20180901 18
<h4>Motivation</h4>Transmembrane proteins (TMPs) are crucial in the life of the cells. As they have special properties, their structure is hard to determine--the PDB database consists of 2% TMPs, despite the fact that they are predicted to make up to 25% of the human proteome. Crystallization prediction methods were developed to aid the target selection for structure determination, however, there is a need for a TMP specific service.<h4>Results</h4>Here, we present TMCrys, a crystallization pred ...[more]
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