Ontology highlight
ABSTRACT:
SUBMITTER: Satpathy AT
PROVIDER: S-EPMC6138663 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Satpathy Ansuman T AT Brown Ryanne A RA Gomulia Ellen E Briseño Carlos G CG Mumbach Maxwell R MR Pan Zenggang Z Murphy Kenneth M KM Natkunam Yasodha Y Chang Howard Y HY Kim Jinah J
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20180509 9
Distinguishing classical dendritic cells from other myeloid cell types is complicated by the shared expression of cell surface markers. ZBTB46 is a zinc finger and BTB domain-containing transcription factor, which is expressed by dendritic cells and committed dendritic cell precursors, but not by plasmacytoid dendritic cells, monocytes, macrophages, or other immune cell populations. In this study, we demonstrate that expression of ZBTB46 identifies human dendritic cell neoplasms. We examined ZBT ...[more]