Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC6140468 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20180827 37
DNA methylation functions in gene silencing and the maintenance of genome integrity. In plants, non-CG DNA methylation is linked through a self-reinforcing loop with histone 3 lysine 9 dimethylation (H3K9me2). The plant-specific SUPPRESSOR OF VARIEGATION 3-9 HOMOLOG (SUVH) family H3K9 methyltransferases (MTases) bind to DNA methylation marks and catalyze H3K9 methylation. Here, we analyzed the structure and function of <i>Arabidopsis thaliana</i> SUVH6 to understand how this class of enzyme main ...[more]