Ontology highlight
ABSTRACT:
SUBMITTER: Ward RA
PROVIDER: S-EPMC6140579 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Ward Richard A RA Vienken Jörg J Silverstein Douglas M DM Ash Stephen S Canaud Bernard B
Clinical journal of the American Society of Nephrology : CJASN 20180306 9
Online hemodiafiltration provides greater removal of higher molecular weight uremic retention solutes than conventional high-flux hemodialysis. However, online hemodiafiltration is used sparsely in the United States in part because of a paucity of delivery systems cleared for clinical use by the US Food and Drug Administration. Although a pathway for regulatory approval exists in the United States, concerns remain, particularly regarding online production of the large volumes of sterile, nonpyro ...[more]