Unknown

Dataset Information

0

Impact of timing of surgery in elderly hip fracture patients: a systematic review and meta-analysis.


ABSTRACT: We aimed to assess the impact of timing of surgery in elderly patients with acute hip fracture on morbidity and mortality. We systematically searched MEDLINE, the Cochrane Library, Embase, PubMed, and trial registries from 01/1997 to 05/2017, as well as reference lists of relevant reviews, archives of orthopaedic conferences, and contacted experts. Eligible studies had to be randomised controlled trials (RCTs) or prospective cohort studies, including patients 60 years or older with acute hip fracture. Two authors independently assessed study eligibility, abstracted data, and critically appraised study quality. We conducted meta-analyses using the generic inverse variance model. We included 28 prospective observational studies reporting data of 31,242 patients. Patients operated on within 48?hours had a 20% lower risk of dying within 12 months (risk ratio (RR) 0.80, 95% confidence interval (CI) 0.66-0.97). No statistical significant different mortality risk was observed when comparing patients operated on within or after 24?hours (RR 0.82, 95% CI 0.67-1.01). Adjusted data demonstrated fewer complications (8% vs. 17%) in patients who had early surgery, and increasing risk for pressure ulcers with increased time of delay in another study. Early hip surgery within 48?hours was associated with lower mortality risk and fewer perioperative complications.

SUBMITTER: Klestil T 

PROVIDER: S-EPMC6141544 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

altmetric image

Publications

Impact of timing of surgery in elderly hip fracture patients: a systematic review and meta-analysis.

Klestil Thomas T   Röder Christoph C   Stotter Christoph C   Winkler Birgit B   Nehrer Stefan S   Lutz Martin M   Klerings Irma I   Wagner Gernot G   Gartlehner Gerald G   Nussbaumer-Streit Barbara B  

Scientific reports 20180917 1


We aimed to assess the impact of timing of surgery in elderly patients with acute hip fracture on morbidity and mortality. We systematically searched MEDLINE, the Cochrane Library, Embase, PubMed, and trial registries from 01/1997 to 05/2017, as well as reference lists of relevant reviews, archives of orthopaedic conferences, and contacted experts. Eligible studies had to be randomised controlled trials (RCTs) or prospective cohort studies, including patients 60 years or older with acute hip fra  ...[more]

Similar Datasets

| S-EPMC9133882 | biostudies-literature
| S-EPMC5557195 | biostudies-literature
| S-EPMC6286489 | biostudies-literature
| S-EPMC10069416 | biostudies-literature
| S-EPMC10957669 | biostudies-literature
| S-EPMC7408859 | biostudies-literature
| S-EPMC5099561 | biostudies-literature
| S-EPMC2952007 | biostudies-other
| S-EPMC6919429 | biostudies-literature
| S-EPMC9280195 | biostudies-literature