Super-resolution ultrasound imaging method for microvasculature in vivo with a high temporal accuracy.

ABSTRACT: Traditional ultrasound imaging techniques are limited in spatial resolution to visualize angiogenic vasa vasorum that is considered as an important marker for atherosclerotic plaque progression and vulnerability. The recently introduced super-resolution imaging technique based on microbubble center localization has shown potential to achieve unprecedented high spatial resolution beyond the acoustic diffraction limit. However, a major drawback of the current super-resolution imaging approach is low temporal resolution because it requires a large number of imaging frames. In this study, a new imaging sequence and signal processing approach for super-resolution ultrasound imaging are presented to improve temporal resolution by employing deconvolution and spatio-temporal-interframe-correlation

SUBMITTER: Yu J 

PROVIDER: S-EPMC6141566 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature