InterCells: A Generic Monte-Carlo Simulation of Intercellular Interfaces Captures Nanoscale Patterning at the Immune Synapse.
Ontology highlight
ABSTRACT:
SUBMITTER: Neve-Oz Y
PROVIDER: S-EPMC6141710 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
InterCells: A Generic Monte-Carlo Simulation of Intercellular Interfaces Captures Nanoscale Patterning at the Immune Synapse.
Neve-Oz Yair Y Sajman Julia J Razvag Yair Y Sherman Eilon E
Frontiers in immunology 20180911
Molecular interactions across intercellular interfaces serve to convey information between cells and to trigger appropriate cell functions. Examples include cell development and growth in tissues, neuronal and immune synapses (ISs). Here, we introduce an agent-based Monte-Carlo simulation of user-defined cellular interfaces. The simulation allows for membrane molecules, embedded at intercellular contacts, to diffuse and interact, while capturing the topography and energetics of the plasma membra ...[more]
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