Ontology highlight
ABSTRACT:
SUBMITTER: Ghanta M
PROVIDER: S-EPMC6143352 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Ghanta Mohankrishna M Panchanathan Elango E Lakkakula Bhaskar Venkata Kameswara Subrahmanya BVKS Narayanaswamy Anbumani A Abhinand P A PA Antony Stalin S
Bioinformation 20180731 7
Soluble guanylate cyclase (sGC) is a type of lyase enzyme with profoundly increasing importance in treatments of cardiovascular and neurodegenerative disorders. Modulation of sGC activity demonstrated beneficial effects against Parkinson's disease by reducing glutamate excitotoxicity. It is of interest to evaluate the pharmacological activity of Momordica charantia phytoconstituent (DGalacturonic acid) and ODQ with catalytic domain of sGC enzyme, using Autodock version 4.2 programs. Docking resu ...[more]