Social Responsiveness Scale (SRS) in Relation to Longitudinal Cortical Thickness Changes in Autism Spectrum Disorder.
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ABSTRACT:
SUBMITTER: Prigge MBD
PROVIDER: S-EPMC6143416 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
Social Responsiveness Scale (SRS) in Relation to Longitudinal Cortical Thickness Changes in Autism Spectrum Disorder.
Prigge Molly B D MBD Bigler Erin D ED Travers Brittany G BG Froehlich Alyson A Abildskov Tracy T Anderson Jeffrey S JS Alexander Andrew L AL Lange Nicholas N Lainhart Janet E JE Zielinski Brandon A BA
Journal of autism and developmental disorders 20181001 10
The relationship between brain development and clinical heterogeneity in autism (ASD) is unknown. This study examines the Social Responsiveness Scale (SRS) in relation to the longitudinal development of cortical thickness. Participants (N = 91 ASD, N = 56 TDC; 3-39 years at first scan) were scanned up to three times over a 7-year period. Mixed-effects models examined cortical thickness in relation to SRS score. ASD participants with higher SRS scores showed regionally increased age-related corti ...[more]
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