Ontology highlight
ABSTRACT:
SUBMITTER: Dong X
PROVIDER: S-EPMC6144810 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Dong Xiaolong X Ranganathan Srivathsan S Qu Guosheng G Piazza Carol Lyn CL Belfort Marlene M
Nucleic acids research 20180901 16
Group II introns, the putative progenitors of spliceosomal introns and retrotransposons, are ribozymes that are capable of self-splicing and DNA invasion. In the cell, group II introns form ribonucleoprotein (RNP) complexes with an intron-encoded protein, which is essential to folding, splicing and retromobility of the intron. To understand the structural accommodations underlying splicing, in preparation for retromobility, we probed the endogenously expressed Lactococcus lactis Ll.LtrB group II ...[more]