Mechanosensation: A Catch Bond That Only Hooks One Way.
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ABSTRACT:
SUBMITTER: Swaminathan V
PROVIDER: S-EPMC6145086 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Publications
Mechanosensation: A Catch Bond That Only Hooks One Way.
Swaminathan Vinay V Alushin Gregory M GM Waterman Clare M CM
Current biology : CB 20171101 21
Single-molecule force spectroscopy and modeling have revealed that the adhesion molecule vinculin and F-actin form a catch bond that is dependent on the direction of forces along the actin filament. This may underlie the mechanisms by which cells sense directional physical cues. ...[more]
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