Ontology highlight
ABSTRACT:
SUBMITTER: Staley C
PROVIDER: S-EPMC6145197 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Staley Christopher C Kaiser Thomas T Vaughn Byron P BP Graiziger Carolyn T CT Hamilton Matthew J MJ Rehman Tauseef Ur TU Song Kevin K Khoruts Alexander A Sadowsky Michael J MJ
Microbiome 20180918 1
<h4>Background</h4>Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridium difficile infection (rCDI). The use of freeze-dried, encapsulated donor material for FMT (cap-FMT) allows for an easy route of administration and remains clinically effective in the majority of rCDI patients. We hypothesized that specific shifts in the microbiota in response to cap-FMT could predict clinical outcome. We further evaluated the degree of donor microbiota engraftment to dete ...[more]