Multiple Myeloma and Its Precursor Disease Among Firefighters Exposed to the World Trade Center Disaster.

ABSTRACT:

Importance

The World Trade Center (WTC) attacks on September 11, 2001, created an unprecedented environmental exposure to known and suspected carcinogens suggested to increase the risk of multiple myeloma. Multiple myeloma is consistently preceded by the precursor states of monoclonal gammopathy of undetermined significance (MGUS) and light-chain MGUS, detectable in peripheral blood.

Objective

To characterize WTC-exposed firefighters with a diagnosis of multiple myeloma and to conduct a screening study for MGUS and light-chain MGUS.

Design, setting, and participants

Case series of multiple myeloma in firefighters diagnosed between September 11, 2001, and July 1, 2017, together with a seroprevalence study of MGUS in serum samples collected from Fire Department of the C

SUBMITTER: Landgren O 

PROVIDER: S-EPMC6145680 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature