MTP genetic variants associated with non-alcoholic fatty liver in metabolic syndrome patients.
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ABSTRACT:
SUBMITTER: Gouda W
PROVIDER: S-EPMC6147179 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
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MTP genetic variants associated with non-alcoholic fatty liver in metabolic syndrome patients.
Gouda Weaam W Ashour Esmat E Shaker Yehia Y Ezzat Wafaa W
Genes & diseases 20171016 4
This study was performed for investigation the relationship between variants of MTP gene polymorphism and the development of NAFLD in patients with and without MS. The study was included 174 NAFLD patients (106 with MS and 68 without MS), and 141 healthy control subjects. The 493 G/T polymorphism of MTP gene was evaluated by PCR-RFLP method. The frequency of MTP TT genotype and T allele were significantly higher in NAFLD patients when compared to healthy controls. Moreover, a significant associa ...[more]
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