Reference intervals for common biochemistry laboratory tests in the Saudi population by a direct a priori method.
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ABSTRACT: Background
Reference intervals (RI) for biochemistry laboratory tests are now based on Caucasian rather than Saudi populations. Test parameters may vary because of race, lifestyle, population structure and geographic location.Objectives
To establish reference intervals for common clinical chemistry laboratory tests for the Saudi population.Design
Direct a priori method.Setting
Tertiary care hospital.Materials and methods
Blood samples were taken from 625 individuals aged from 2 to 87 years from different geographic areas for 93 biochemistry tests. RIs were established following the International Federation of Clinical Chemistry guideline.Main outcome measure(s)
Reference values for common biochemistry lab tests.Results
Ninety-three age- or gender-stratified reference intervals (RIs) based on the Saudi population were established. There were 72 non-partitioned tests. Most of the tests were similar to RIs from manufacturer's inserts. For some sex hormones (estrogen, luteinizing hormone, follicle-stimulating hormone, progesterone and 17 alpha-Hydroxyprogesterone) only male RIs were established as there were not enough samples to stratify for females based on physiologic status.Conclusion
The RIs are reliable and applicable to a general Saudi population.Limitations
Due to the sample size, RIs were not generated for some sex hormones for females.
SUBMITTER: Hu XL
PROVIDER: S-EPMC6148986 | biostudies-literature |
REPOSITORIES: biostudies-literature
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