Ontology highlight
ABSTRACT:
SUBMITTER: Tisovsky P
PROVIDER: S-EPMC6150331 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Tisovský Pavol P Šandrik Róbert R Horváth Miroslav M Donovalová Jana J Filo Juraj J Gáplovský Martin M Jakusová Klaudia K Cigáň Marek M Sokolík Róbert R Gáplovský Anton A
Molecules (Basel, Switzerland) 20171114 11
Five isatin anions were prepared by deprotonation of initial isatins in aprotic solvents using basic fluoride and acetate anions (F<sup>-</sup> and CH₃COO<sup>-</sup>). The F<sup>-</sup> basicity is sufficient to deprotonate isatin NH hydrogen from all the studied compounds. This process is reversible. In the presence of proton donor solvents, the anions form the corresponding isatins. The isatin hydrogen acidity depends on the overall structure of the isatin derivatives. The anions were charact ...[more]