Ontology highlight
ABSTRACT:
SUBMITTER: Yin J
PROVIDER: S-EPMC6151655 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Yin Juxin J Wang Bingmei B Zhu Xuejun X Qu Xiaonan X Huang Yi Y Lv Shaowu S Mu Ying Y Luo Guimin G
Molecules (Basel, Switzerland) 20170908 9
Glutathione peroxidase (GPx) is an antioxidant protein containing selenium. Owing to the limitations of native GPx, considerable efforts have been made to develop GPx mimics. Here, a short 5-mer peptides (5P) was synthesized and characterized using matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Enzyme coupled assays were used to evaluate GPx activity. The cell viability and apoptosis of H22 cells were tested, and mice bearing H22 cell-derived tumors were used to de ...[more]