Ontology highlight
ABSTRACT:
SUBMITTER: Chen C
PROVIDER: S-EPMC6152258 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20170804 8
A simple and efficient method for the synthesis of spiro[indoline-3,9'-xanthene]trione derivatives by means of condensation between isatins and 1,3-cyclohexanedione in the presence of a catalytic amount of magnesium perchlorate at 80 °C in 50% aqueous ethanol medium has been described. Notably, the present method offers desirable advantages of good yields, simplicity of workup procedure, easy purification, and reduced reaction times. ...[more]