Ontology highlight
ABSTRACT:
SUBMITTER: Fei X
PROVIDER: S-EPMC6152652 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20170529 6
Gallic acid (3,4,5-trihydroxybenzoic acid), is a natural product found in various foods and herbs that are well known as powerful antioxidants. Our previous report demonstrated that it inhibits mast cell-derived inflammatory allergic reactions by blocking histamine release and pro-inflammatory cytokine expression. In this report, various amide analogs of gallic acid have been synthesized by introducing different amines through carbodiimide-mediated amide coupling and Pd/C-catalyzed hydrogenation ...[more]