Ontology highlight
ABSTRACT:
SUBMITTER: Weile J
PROVIDER: S-EPMC6153521 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Human genetics 20180802 9
Given the constantly improving cost and speed of genome sequencing, it is reasonable to expect that personal genomes will soon be known for many millions of humans. This stands in stark contrast with our limited ability to interpret the sequence variants which we find. Although it is, perhaps, easiest to interpret variants in coding regions, knowledge of functional impact is unknown for the vast majority of missense variants. While many computational approaches can predict the impact of coding v ...[more]