Ontology highlight
ABSTRACT:
SUBMITTER: Hanna JR
PROVIDER: S-EPMC6154328 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Hanna Jill R JR Allan Christopher C Lawrence Charlotte C Meyer Odile O Wilson Neil D ND Hulme Alison N AN
Molecules (Basel, Switzerland) 20170514 5
The CuAAC 'click' reaction was used to couple alkyne-functionalized lanthanide-DOTA complexes to a range of fluorescent antennae. Screening of the antenna components was aided by comparison of the luminescent output of the resultant sensors using data normalized to account for reaction conversion as assessed by IR. A maximum 82-fold enhanced signal:background luminescence output was achieved using a Eu(III)-DOTA complex coupled to a coumarin-azide, in a reaction which is specific to the presence ...[more]