Ontology highlight
ABSTRACT:
SUBMITTER: Chudzik M
PROVIDER: S-EPMC6155906 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Chudzik Mariola M Maciążek-Jurczyk Małgorzata M Pawełczak Bartosz B Sułkowska Anna A
Molecules (Basel, Switzerland) 20161227 1
Pathological states in the organism, e.g., renal or hepatic diseases, cataract, dysfunction of coronary artery, diabetes mellitus, and also intensive workout, induce the structural modification of proteins called molecular ageing or N-A isomerization. The aim of this study was to analyze the structural changes of serum albumin caused by alkaline ageing using absorption, spectrofluorescence, and circular dichroism spectroscopy. The N-A isomerization generates significant changes in bovine (BSA) a ...[more]