Meta-analysis of the impact of postoperative complications on survival after oesophagectomy for cancer.

ABSTRACT:

Background

Oesophagectomy has a high risk of postoperative morbidity. The impact of postoperative complications on overall survival of oesophageal cancer remains unclear. This meta-analysis addressed the impact of complications on long-term survival following oesophagectomy.

Methods

A search of PubMed and Cochrane Library databases was undertaken for systematic review of papers published between January 1995 and August 2016 that analysed the relation between postoperative complications and long-term survival. In the meta-analysis, data were pooled. The main outcome was overall survival (OS). Secondary endpoints included disease-free (DFS) and cancer-specific (CSS) survival.

Results

A total of 357 citations was reviewed; 21 studies comprising 11 368 patients were inclu

SUBMITTER: Booka E 

PROVIDER: S-EPMC6156161 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature