Ontology highlight
ABSTRACT:
SUBMITTER: Bodker JS
PROVIDER: S-EPMC6156884 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Bødker Julie Støve JS Brøndum Rasmus Froberg RF Schmitz Alexander A Schönherz Anna Amanda AA Jespersen Ditte Starberg DS Sønderkær Mads M Vesteghem Charles C Due Hanne H Nørgaard Caroline Holm CH Perez-Andres Martin M Samur Mehmet Kemal MK Davies Faith F Walker Brian B Pawlyn Charlotte C Kaiser Martin M Johnson David D Bertsch Uta U Broyl Annemiek A van Duin Mark M Shah Rajen R Johansen Preben P Nørgaard Martin Agge MA Samworth Richard J RJ Sonneveld Pieter P Goldschmidt Hartmut H Morgan Gareth J GJ Orfao Alberto A Munshi Nikhil N Johnson Hans Erik HE El-Galaly Tarec T Dybkær Karen K Bøgsted Martin M
Blood advances 20180901 18
Despite the recent progress in treatment of multiple myeloma (MM), it is still an incurable malignant disease, and we are therefore in need of new risk stratification tools that can help us to understand the disease and optimize therapy. Here we propose a new subtyping of myeloma plasma cells (PCs) from diagnostic samples, assigned by normal B-cell subset associated <u>g</u>ene signatures (BAGS). For this purpose, we combined fluorescence-activated cell sorting and gene expression profiles from ...[more]