Niche partitioning of a pathogenic microbiome driven by chemical gradients.
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ABSTRACT:
SUBMITTER: Quinn RA
PROVIDER: S-EPMC6157970 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Publications
Niche partitioning of a pathogenic microbiome driven by chemical gradients.
Quinn Robert A RA Comstock William W Zhang Tianyu T Morton James T JT da Silva Ricardo R Tran Alda A Aksenov Alexander A Nothias Louis-Felix LF Wangpraseurt Daniel D Melnik Alexey V AV Ackermann Gail G Conrad Douglas D Klapper Isaac I Knight Rob R Dorrestein Pieter C PC
Science advances 20180926 9
Environmental microbial communities are stratified by chemical gradients that shape the structure and function of these systems. Similar chemical gradients exist in the human body, but how they influence these microbial systems is more poorly understood. Understanding these effects can be particularly important for dysbiotic shifts in microbiome structure that are often associated with disease. We show that pH and oxygen strongly partition the microbial community from a diseased human lung into ...[more]
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