Ontology highlight
ABSTRACT:
SUBMITTER: Van Egeren D
PROVIDER: S-EPMC6158234 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Van Egeren Debra D Madsen Thomas T Michor Franziska F
Communications biology 20180926
Individuals in a population often have different fitnesses even when they have identical genotypes, but the effect of this variation on the evolution of a population through complicated fitness landscapes is unknown. Here, we investigate how populations with non-genetic fitness variation cross fitness valleys, common barriers to adaptation in rugged fitness landscapes in which a population must pass through a deleterious intermediate to arrive at a final advantageous stage. We develop a stochast ...[more]