Ontology highlight
ABSTRACT:
SUBMITTER: Velthorst E
PROVIDER: S-EPMC6158250 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Translational psychiatry 20180926 1
While psychotic experiences (PEs) are assumed to represent psychosis liability, general population studies have not been able to establish significant associations between polygenic risk scores (PRS) and PEs. Previous work suggests that PEs may only represent significant risk when accompanied by social impairment. Leveraging data from the large longitudinal IMAGEN cohort, including 2096 14-year old adolescents that were followed-up to age 18, we tested whether the association between polygenic r ...[more]