Ontology highlight
ABSTRACT:
SUBMITTER: Rochat T
PROVIDER: S-EPMC6158497 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Nucleic acids research 20180901 17
RsaE is a regulatory RNA highly conserved amongst Firmicutes that lowers the amount of mRNAs associated with the TCA cycle and folate metabolism. A search for new RsaE targets in Staphylococcus aureus revealed that in addition to previously described substrates, RsaE down-regulates several genes associated with arginine catabolism. In particular, RsaE targets the arginase rocF mRNA via direct interactions involving G-rich motifs. Two duplicated C-rich motifs of RsaE can independently downregulat ...[more]