Ontology highlight
ABSTRACT:
SUBMITTER: Maurin T
PROVIDER: S-EPMC6158598 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Nucleic acids research 20180701 12
Fragile X syndrome (FXS), the most common form of inherited intellectual disability, is due to the functional deficiency of the fragile X mental retardation protein (FMRP), an RNA-binding protein involved in translational regulation of many messenger RNAs, playing key roles in synaptic morphology and plasticity. To date, no effective treatment for FXS is available. We searched for FMRP targets by HITS-CLIP during early development of multiple mouse brain regions (hippocampus, cortex and cerebell ...[more]