Ontology highlight
ABSTRACT:
SUBMITTER: Powell CR
PROVIDER: S-EPMC6159213 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20180426 21
Persulfides (RSSH) have been hypothesized as critical components in sulfur-mediated redox cycles and as potential signaling compounds, similar to hydrogen sulfide (H<sub>2</sub> S). Hindering the study of persulfides is a lack of persulfide-donor compounds with selective triggers that release discrete persulfide species. Reported here is the synthesis and characterization of a ROS-responsive (ROS=reactive oxygen species), self-immolative persulfide donor. The donor, termed BDP-NAC, showed select ...[more]