Ankyrin domain encoding genes from an ancient horizontal transfer are functionally integrated into Nasonia developmental gene regulatory networks.

ABSTRACT:

Background

How regulatory networks incorporate additional components and how novel genes are functionally integrated into well-established developmental processes are two important and intertwined questions whose answers have major implications for understanding the evolution of development. We recently discovered a set of lineage-restricted genes with strong and specific expression patterns along the dorsal-ventral (DV) axis of the embryo of the wasp Nasonia that may serve as a powerful system for addressing these questions. We sought to both understand the evolutionary history of these genes and to determine their functions in the Nasonia DV patterning system.

Results

We have found that the novel DV genes are part of a large family of rapidly duplicating and diverging anky

SUBMITTER: Pers D 

PROVIDER: S-EPMC6161386 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature