Ontology highlight
ABSTRACT:
SUBMITTER: Larson EL
PROVIDER: S-EPMC6161750 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Larson Erica L EL Kopania Emily E K EEK Good Jeffrey M JM
Trends in genetics : TIG 20180801 9
Developmental constraint and sexual conflict shape the evolution of heteromorphic sex chromosomes. These contrasting forces are perhaps strongest during spermatogenesis in species with XY males. In this review, we consider how the unique regulatory environment and selective pressures of spermatogenesis interact to impact sex chromosome evolution in mammals. We explore how each developmental phase of spermatogenesis influences sex chromosome gene content, structure, and rate of molecular evolutio ...[more]